During the 80’s, it was common to replace 3 embryos to increase the chances of pregnancy. However, this method may lead to twin or triple pregnancy.

Multiple pregnancies may present a greater risk of complications, particularly premature birth.

For this reason, doctors have always tried to reduce the risk of multiple pregnancies without reducing the chance of success.

Nevertheless, the chance of twin births in 1996 was 18 times higher and the risk of triplet births was 43 times higher with the application of assisted reproductive technology than that of natural risk.