The successful pregnancy rate for intra-uterine insemination (IUI) varies considerably; it depends on the age of female partner, the type of ovarian stimulation used if any, the duration of infertility, the causes of infertility, the number and quality of motile sperm in the sperm preparation specimen, and other factors.
Generally the pregnancy rate is around 15-20% per IUI cycle. In our experience, we provide the “Wang Tube Real-Time Sperm Micro-Separation System”; we achieve a better pregnancy rate for our patients. Many couples with long years of history of infertility (up to 15 years), they became pregnant at the first attempt of IUI.
The pregnancy rate for women over age 35 drops, and for women over age 40 are much lower. When in vivo artificial insemination (AI) is applied, pregnancy rate is lower, if the female partner is over 40, poor function of ovulation, poor quality of oocyte formation, poor sperm quality and number, moderate or severe endometriosis, any tubal damage, pelvic adhesion, or long term history of infertility (more than 3 years).
The pregnancy rate is higher for women who do not ovulate by themselves primarily without the aid of medication but can ovulate well with medications and then receive artificial insemination (AI), such as intrauterine insemination (IUI).
For a couple with unexplained infertility, female age greater than 35, trying for 2 years by nature, and normal semen parameters, it is generally expected that pregnancy rate is about 8-10% per month by given ovarian stimulation medications (e.g., clomiphene, follistim or pergonal) with intrauterine insemination (IUI), while pregnancy rate may reach 40-50% per in vitro fertilization (IVF) treatment cycle.